We do streaming in a bar where sometimes there is a Jukebox playing music. I can get a direct feed from the jukebox as an audio source if I like.

I am wondering if there is anyone who knows you to dynamically remove the audio that is coming from multiple mics/inputs where one would be the source of sound to cancel, the others would contain the content plus the sound to cancel?

Anyone have ideas?

if you are talking about removing jukebox audio bleeding into microphones as a background sound, you could try gating the microphones.. if the jukebox signal is fairly low and the people speaking in the mics are fairly loud that might work ok..

there is also some VST plugins which claim to help with background noise.. i havent tried any but i saw a Youtube video the other day on Goyo Voice Seperator which looked interesting.. could be worth checking out..