You have 5 layers, so if you use one for the background, one for the talent, one for a desk in front of the talent, you have 2 left for screens.
If you only use a background and a talent, you can have 3 different screens.
If you want to take it up to more, you need to setup your background with screens trough multiview on a separate input and set that as the virtual set background.

You can also build the virtual set from inputs using multiview with some virtual inputs, set the zoom and XYZ coordinates on the inputs and do the camera movements trough the merge transition.
That way you would benefit from easy controls and the ability to see the different shots in the multiviewer.