Bizarre issue: this is not affecting v26 on same computer. I've been testing 27pvw for several days. Starting yesterday, if I open a file with some graphics and a video, it plays fine for 20 seconds, but at that point, the video continues to play audio, but the picture is a solid dark brown; jpg inputs show as solid white; png and gtzip files as solid black; color bars as grey; and NDI as deep blue.
Running 27.0.0.52

Alienware Aurora R11
Intel i9 3.70GHz
32GB RAM
Windows 10Pro
NVIDIA GeForce RTX 2080Ti

This was not happening for the first 2 days after I had updated to .52

Up until then, I was loving everything I saw in the new version. Look forward to release!

(20 minutes later)
Seem to have fixed this, we changed our audio board (USB connection). Our B,C and D buss outputs did not get changed. I reset them in audio outputs and it all seems working. Didn't occur to me that audio setting would effect video that way.

Next morning: Issue has returned.

Had time to do a clean re-install and everything seems to be good.